Clinical data
Routes of
ATC code none
Legal status
Legal status
  • Uncontrolled
CAS Number 76716-60-4
PubChem (CID) 71153
ChemSpider 64297
UNII 713BBL6840 YesY
Chemical and physical data
Formula C14H19F3N4O
Molar mass 316.151 g/mol
3D model (Jmol) Interactive image

Fluprazine (DU-27,716) is a drug of the phenylpiperazine class. It is a so-called serenic or antiaggressive agent.[1] It is closely related to several other piperazines, including eltoprazine and batoprazine, and TFMPP, as well as more distantly to the azapirones such as buspirone. The pharmacology of fluprazine is unknown, but it is likely to act as an agonist at the 5-HT1A and 5-HT1B receptors like its sister compound eltoprazine.

See also


  1. van der Poel AM, Olivier B, Mos J, Kruk MR, Meelis W, van Aken JH (1982). "Anti-aggressive effect of a new phenylpiperazine compound (DU27716) on hypothalamically induced behavioural activities.". Pharmacol Biochem Behav. 17 (1): 147–153. doi:10.1016/0091-3057(82)90277-5. PMID 6889746.
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