Clinical data
AHFS/Drugs.com International Drug Names
Routes of
By mouth
ATC code N05AE01 (WHO)
Legal status
Legal status
  • ℞ (Prescription only)
CAS Number 153-87-7 YesY
PubChem (CID) 4640
ChemSpider 4479 N
KEGG D01219 YesY
ECHA InfoCard 100.005.291
Chemical and physical data
Formula C23H29N3O2
Molar mass 379.49 g/mol
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

Oxypertine (Equipertine, Forit, Integrin, Lanturil, Lotawin, Opertil) is an antipsychotic used in the treatment of schizophrenia.[1] It was also evaluated for the treatment of anxiety at a dosage of 20 mg per day.[2] Chemically, it is an indole derivative similarly to molindone and a member of the phenylpiperazine class.[3] Like reserpine and tetrabenazine, oxypertine depletes catecholamines, though not serotonin, possibly underlying its neuroleptic efficacy.[4] The molecular structure is strongly similar to solypertine and milipertine.


  1. Hall, Chapman and; Rhodes, P. H (1996). Dictionary of organic compounds. London: Chapman & Hall. ISBN 0-412-54090-8.
  2. Somohano MD, Broissin MC, Sobrino z A. [Clinical evaluation of oxypertine in anxiety conditions]. Neurol Neurocir Psiquiatr. 1976;17(3):171-80.
  3. Breulet M, Labar P, Delree C, Collard J, Bobon J (February 1968). "[Oxypertine, peperazine derivative of tryptophan with neuroleptic and dynamogenic properties]". Acta Neurol Psychiatr Belg (in French). 68 (2): 116–27. PMID 4972600.
  4. Bak IJ, Hassler R, Kim JS (1969). "Differential monoamine depletion by oxypertine in nerve terminals. Granulated synaptic vesicles in relation to depletion of norepinephrine, dopamine and serotonin". Zeitschrift für Zellforschung und Mikroskopische Anatomie (Vienna, Austria : 1948). 101 (3): 448–62. PMID 5362847.
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