|Chemical and physical data|
|Molar mass||317.769 g/mol|
|3D model (Jmol)||Interactive image|
6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide (CEPC) is a drug which acts as a potent and selective antagonist for the serotonin 5-HT2C receptor. In animal studies it was found to potentiate the conditioned place preference induced by low-dose amphetamine, demonstrating that 5-HT2C-mediated disinhibition of dopamine release can cause interactions with dopaminergic drugs.
- McCorvy JD, Harland AA, Maglathlin R, Nichols DE. A 5-HT(2C) receptor antagonist potentiates a low dose amphetamine-induced conditioned place preference. Neuroscience Letters. 2011 Nov 7;505(1):10-3. PMID 21827831