Chemical and physical data
Formula C16H16ClN3O2
Molar mass 317.769 g/mol
3D model (Jmol) Interactive image

6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide (CEPC) is a drug which acts as a potent and selective antagonist for the serotonin 5-HT2C receptor. In animal studies it was found to potentiate the conditioned place preference induced by low-dose amphetamine, demonstrating that 5-HT2C-mediated disinhibition of dopamine release can cause interactions with dopaminergic drugs.[1]

See also


  1. McCorvy JD, Harland AA, Maglathlin R, Nichols DE. A 5-HT(2C) receptor antagonist potentiates a low dose amphetamine-induced conditioned place preference. Neuroscience Letters. 2011 Nov 7;505(1):10-3. PMID 21827831
This article is issued from Wikipedia - version of the 3/22/2013. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.