CAS Number 20229-30-5
PubChem (CID) 4106
ChemSpider 3963
UNII 55D94103HL YesY
Chemical and physical data
Formula C20H24N2S2
Molar mass 356.55 g/mol
3D model (Jmol) Interactive image

Metitepine (INN), also commonly known as methiothepin, is a tricyclic described as a psychotropic agent that acts as an non-selective antagonist of various serotonin and dopamine receptors.[1][2][3] It has antipsychotic properties.[4]

See also


  1. J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 815–. ISBN 978-1-4757-2085-3.
  2. Monachon MA, Burkard WP, Jalfre M, Haefely W (1972). "Blockade of central 5-hydroxytryptamine receptors by methiothepin". Naunyn Schmiedebergs Arch. Pharmacol. 274 (2): 192–7. doi:10.1007/BF00501854. PMID 4340797.
  3. Dall'Olio R, Vaccheri A, Montanaro N (1985). "Reduced head-twitch response to quipazine of rats previously treated with methiothepin: possible involvement of dopaminergic system". Pharmacol. Biochem. Behav. 23 (1): 43–8. doi:10.1016/0091-3057(85)90128-5. PMID 2994121.
  4. Thomas L. Lemke; David A. Williams (24 January 2012). Foye's Principles of Medicinal Chemistry. Lippincott Williams & Wilkins. pp. 388–. ISBN 978-1-60913-345-0.

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