Clinical data
  • N (US)
Routes of
Oral, nasal, IV
Legal status
Legal status
CAS Number 1112937-64-0 N
PubChem (CID) 57252245
ChemSpider 21106271 N
Chemical and physical data
Formula C12H15NO3
Molar mass 221.2524 g/mol
3D model (Jmol) Interactive image
Chirality Racemic mixture
 NYesY (what is this?)  (verify)

Ethylone, also known as 3,4-methylenedioxy-N-ethylcathinone (MDEC, βk-MDEA), is recreational designer drug classified as an entactogen, stimulant, and psychedelic of the phenethylamine, amphetamine, and cathinone chemical classes. It is the β-keto analogue of MDEA ("Eve"). Ethylone has only a short history of human use and is reported to be less potent than its relative methylone. In the United States, it began to be found in cathinone products in late 2011.[1]

Very little data exists about the pharmacological properties, metabolism, and toxicity of ethylone, but several ethylone-related deaths have been reported.[1]


Analysis of human and rat urine for the metabolites of bk-amphetamines suggested that ethylone was degraded in the following metabolic steps:[2]

  1. N-deethylation to the primary amine.
  2. Reduction of the keto moiety to the respective alcohol.

As of October 2015 Ethylone is a controlled substance in China.[3]

See also


  1. 1 2 Dayong Lee; Chris W. Chronister; Jennifer Hoyer; Bruce A. Goldberger (September 2015). "Ethylone-Related Deaths: Toxicological Findings". Journal of Analytical Toxicology. 39 (7): 567–571. doi:10.1093/jat/bkv053. PMID 26025164.
  2. Meyer, Markus R; Jens Wilhelm; Frank T. Peters; Hans H. Maurer (June 2010). "Beta-keto amphetamines: studies on the metabolism of the designer drug mephedrone and toxicological detection of mephedrone, butylone, and methylone in urine using gas chromatography–mass spectrometry". Analytical and Bioanalytical Chemistry. 397 (3): 1225–1233. doi:10.1007/s00216-010-3636-5. PMID 20333362.
  3. "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Retrieved 1 October 2015.

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