PubChem (CID) 2737389
ChemSpider 2019031 YesY
Chemical and physical data
Formula C16H18N2
Molar mass 238.327 g/mol
3D model (Jmol) Interactive image

1-(2-Diphenyl)piperazine, also known as RA-7, is a drug which acts as a potent and selective agonist at the 5HT7 serotonin receptor. It was discovered as an active metabolite of the synthetic 5-HT7 agonists LP-12 and LP-211, and unexpectedly turned out to be a similarly potent agonist with selectivity approaching that of the parent molecules, despite its much simpler structure.[1]

See also


  1. Hedlund PB, Leopoldo M, Caccia S, Sarkisyan G, Fracasso C, Martelli G, Lacivita E, Berardi F, Perrone R (August 2010). "LP-211 is a brain penetrant selective agonist for the serotonin 5-HT(7) receptor". Neuroscience Letters. 481 (1): 12–6. doi:10.1016/j.neulet.2010.06.036. PMC 2910240Freely accessible. PMID 20600619.
This article is issued from Wikipedia - version of the 5/12/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.