Clinical data
ATC code none
Legal status
Legal status
  • Non-regulated
CAS Number 925448-93-7
925447-04-7 (hydrochloride)
PubChem (CID) 16071605
ChemSpider 17231095
KEGG D10099 YesY
Chemical and physical data
Formula C22H23N3O3S
Molar mass 409.501 g/mol
3D model (Jmol) Interactive image

Cerlapirdine (USAN; SAM-531, WAY-262,531, PF-05212365) is a drug which is under development by Wyeth/Pfizer for the treatment of cognitive disorders associated with Alzheimer's disease and schizophrenia.[1] As of 2011, it is in phase II clinical trials, and has demonstrated a trend toward efficacy along with a good side effect profile and no incidence of serious adverse events.[2] It exerts its effects by acting as a selective 5-HT6 receptor antagonist.[1]

See also


  1. 1 2 Codony X, Vela JM, Ramírez MJ (February 2011). "5-HT(6) receptor and cognition". Current Opinion in Pharmacology. 11 (1): 94–100. doi:10.1016/j.coph.2011.01.004. PMID 21330210.
  2. Franco Borsini (2011). International review of neurobiology: Pharmacology of 5-HT6 receptors. Part 2. Academic Press. p. 5. ISBN 978-0-12-385902-0. Retrieved 25 October 2011.
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