Clinical data
Trade names Eucapil
Routes of
CAS Number 260980-89-0
PubChem (CID) 44147451
ChemSpider 8106619
Chemical and physical data
Formula C13H11F6N3O5
Molar mass 403.233959 g/mol
3D model (Jmol) Interactive image
Not to be confused with tolbutamide.

Topilutamide (INN), known more commonly as fluridil (brand name Eucapil), is a topical non-steroidal antiandrogen marketed by Interpharma Praha which is used in a number of European countries in the treatment of androgenic alopecia.[1][2][3][4][5] Sold as Eucapil, it is available as a 2% topical formulation intended for application to the scalp.[4] The drug was launched in 2003,[6] and is marketed in the Czech Republic and Slovakia.[7]

See also


  1. Sovak M, Seligson AL, Kucerova R, Bienova M, Hajduch M, Bucek M (2002). "Fluridil, a rationally designed topical agent for androgenetic alopecia: first clinical experience". Dermatol Surg. 28 (8): 678–85. doi:10.1046/j.1524-4725.2002.02017.x. PMID 12174057.
  2. Robert S. Haber; Dowling Bluford Stough (2006). Hair Transplantation. Elsevier Health Sciences. pp. 7–. ISBN 1-4160-3104-9.
  3. Scripta Medica. 2006. pp. 45, 53–54.
  4. 1 2 Marc R. Avram; Nicole E. Rogers (30 November 2009). Hair Transplantation. Cambridge University Press. pp. 11–. ISBN 978-1-139-48339-1.
  5. Kirby RS, Carson CC, Kirby MG, White A (29 January 2009). Men's Health, Third Edition. CRC Press. pp. 362–. ISBN 978-1-4398-0807-8.
  6. Hermkens PH, Kamp S, Lusher S, Veeneman GH (2006). "Non-steroidal steroid receptor modulators". IDrugs. 9 (7): 488–94. PMID 16821162.
  7. Eucapil website

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