Clinical data
ATC code None
Legal status
Legal status
Synonyms SH-489; 1-Methylandrosta-1,4-diene-3,17-dione
CAS Number 96301-34-7 N
PubChem (CID) 57050
ChemSpider 51438 YesY
UNII 62GA3K28B6 YesY
Chemical and physical data
Formula C20H26O2
Molar mass 298.419 g/mol
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

Atamestane (developmental code name SH-489), also known as 1-methylandrosta-1,4-diene-3,17-dione, is a steroidal aromatase inhibitor that was studied in the treatment of cancer. It blocks the production of estrogen in the body. The drug is selective, competitive, and irreversible in its inhibition of aromatase.[1]

See also


  1. el Etreby MF (March 1993). "Atamestane: an aromatase inhibitor for the treatment of benign prostatic hyperplasia. A short review". J. Steroid Biochem. Mol. Biol. 44 (4-6): 565–72. doi:10.1016/0960-0760(93)90260-4. PMID 7682838.

External links

 This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms".

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