Clinical data
Trade names Dostalon, Roxilon
Synonyms Dimethazine, Dymethazine; Dimethasterone azine; Di(methasterone) azine; 2α,17α-Dimethyl-5α-androstan-17β-ol-3-one azine
CAS Number 3625-07-8 YesY
PubChem (CID) 9571069
ChemSpider 16736946 N
UNII 69C642I19V YesY
Chemical and physical data
Formula C42H68N2O2
Molar mass 633.00 g/mol
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

Mebolazine (INN) (brand names Dostalon, Roxilon), also known as dimethazine (di(methasterone) azine) or dymethazine, as well as 2α,17α-dimethyl-5α-androstan-17β-ol-3-one azine, is a synthetic, orally active androgenic-anabolic steroid (AAS) and a 17α-alkylated derivative of dihydrotestosterone (DHT) that is no longer marketed.[1][2] It has a unique and unusual chemical structure, being a dimer of methasterone linked at the 3-position of the A-ring by an azine group, and reportedly acts as a prodrug of methasterone.[3]

See also


  1. J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 756–. ISBN 978-1-4757-2085-3.
  2. Geldof L, Tudela E, Lootens L, van Lysebeth J, Meuleman P, Leroux-Roels G, van Eenoo P, Deventer K (2016). "In vitro and in vivo metabolism studies of dimethazine". Biomed. Chromatogr. 30 (8): 1202–9. doi:10.1002/bmc.3668. PMID 26663462.
  3. Clemens, Roger; Pressman, Peter (2015). "Nutritional and Dietary Supplements: Code or Concern": 47–62. doi:10.1007/978-3-319-22431-2_3.

This article is issued from Wikipedia - version of the 11/30/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.