Bisphenol

The bisphenols (pronounced /ˈbɪs.fᵻ.nɒl/) are a group of chemical compounds with two hydroxyphenyl functionalities. Most of them are based on diphenylmethane. The exceptions are bisphenol S, P, and M. "Bisphenol" is a common name; the letter following refers to one of the reactants. Bisphenol A is the most popular representative of this group, often simply called "bisphenol."

List

Structural formula	Name	CAS	Reactants		Systematic name
	Bisphenol A	80-05-7	Phenol	Acetone	2,2-Bis(4-hydroxyphenyl)propane
	Bisphenol AP	1571-75-1	Phenol	Acetophenone	1,1-Bis(4-hydroxyphenyl)-1-phenyl-ethane
	Bisphenol AF	1478-61-1	Phenol	Hexafluoroacetone	2,2-Bis(4-hydroxyphenyl)hexafluoropropane
	Bisphenol B	77-40-7	Phenol	Butanone	2,2-Bis(4-hydroxyphenyl)butane
	Bisphenol BP	1844-01-5	Phenol	Benzophenone	Bis-(4-hydroxyphenyl)diphenylmethane
	Bisphenol C	79-97-0	Cresol	Acetone	2,2-Bis(3-methyl-4-hydroxyphenyl)propane
	Bisphenol C 2	14868-03-2	Phenol	Dichloromethane	Bis(4-hydroxyphenyl)-2,2-dichlorethylene
	Bisphenol E	2081-08-5	Phenol	Acetaldehyde	1,1-Bis(4-hydroxyphenyl)ethane
	Bisphenol F	87139-40-0	Phenol	Formaldehyde	Bis(4-hydroxyphenyl)methane
	Bisphenol G	127-54-8	2-Isopropylphenol	Acetone	2,2-Bis(4-hydroxy-3-isopropyl-phenyl)propane
	Bisphenol M	13595-25-0			1,3-Bis(2-(4-hydroxyphenyl)-2-propyl)benzene
	Bisphenol S	80-09-1	Phenol	Sulfur trioxide	Bis(4-hydroxyphenyl)sulfone
	Bisphenol P	2167-51-3			1,4-Bis(2-(4-hydroxyphenyl)-2-propyl)benzene
	Bisphenol PH	24038-68-4	2-Phenylphenol	Acetone	5,5’ -(1-Methylethyliden)-bis[1,1’-(bisphenyl)-2-ol]propane
	Bisphenol TMC	129188-99-4	Phenol	3,3,5-Trimethylcyclohexanone	1,1-Bis(4-hydroyphenyl)-3,3,5-trimethyl-cyclohexane
	Bisphenol Z	843-55-0	Phenol	Cyclohexanone	1,1-Bis(4-hydroxyphenyl)-cyclohexane

Bisphenol A diglycidyl ether (BADGE) is another bisphenol derivative, along with EPI-001.

Health effects

Bisphenols A (BPA) and S (BPS) are endocrine disruptors.^[1][2] Due to its high production volumes BPA has been characterised as a "pseudo-persistent" chemical,^[3] leading to its spreading and potential accumulation in a variety of environmental matrices.

Prevention measures

These products tend to release from the material when heated; as a precaution, it is recommended for the consumer:

• not to heat food in a plastic packaging in a microwave oven, or a tin can (its inside coating is often epoxy) with a bain-marie;
• use a pitcher material other than plastic, not a plastic bottle.

References