Clinical data
Routes of
Synonyms 5α-Androst-1-ene-3,17-dione
CAS Number 571-40-4 YesY
PubChem (CID) 11196935
ChemSpider 9372004
UNII C1091EX356
Chemical and physical data
Formula C19H26O2
Molar mass 286.415 g/mol
3D model (Jmol) Interactive image

1-Androstenedione, or 5α-androst-1-ene-3,17-dione, also known as 4,5α-dihydro-δ1-4-androstenedione, is a synthetic androgen and anabolic steroid. It is a 5α-reduced isomer of the endogenous steroid Δ4-androstenedione and acts as an androgen prohormone of 1-testosterone (4,5α-dihydro-δ1-testosterone), a derivative of dihydrotestosterone (DHT).[1]

1-Androstenedione is on the World Anti-Doping Agency's list of prohibited substances,[2] and is therefore banned from use in most major sports.

See also


  1. Zhang H, Qiu Z (December 2006). "An efficient synthesis of 5α-androst-1-ene-3,17-dione". Steroids. 71 (13-14): 1088–90. doi:10.1016/j.steroids.2006.09.008. PMID 17123559.
  2. "The World Anti-Doping Code: The 2012 Prohibited List" (PDF). World Anti-Doping Agency. Retrieved 2012-07-17.

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