Diethylstilbestrol monobenzyl ether

Diethylstilbestrol monobenzyl ether
Clinical data
Trade names Monozol, Hypantin, Pituitrope
Synonyms Benzelstilbestrol
CAS Number 6202-26-2
PubChem (CID) 3036244
ChemSpider 2300304
Chemical and physical data
Formula C25H26O2
Molar mass 358.47274 g/mol
3D model (Jmol) Interactive image

Diethylstilbestrol monobenzyl ether (brand names Monozol, Hypantin, Pituitrope), also known as benzelstilbestrol, is a synthetic, non-steroidal estrogen of the stilbestrol group and an ether of diethylstilbestrol (DES) that is described as a pituitary gland inhibitor (antigonadotropin) and was formerly marketed but is now no longer available.[1][2] It was first synthesized by Wallace & Tiernan Company in 1952, and was described by them as having only weak estrogenic activity.[3] The drug was used to treat gynecological conditions and infertility in women.[2]


  1. J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 397. ISBN 978-1-4757-2085-3.
  2. 1 2 Margaret Marsh; Wanda Ronner (29 December 2010). The Fertility Doctor: John Rock and the Reproductive Revolution. JHU Press. pp. 144–. ISBN 978-1-4214-0208-6.
  3. Ronald George Harrison (1957). Studies on Fertility. Blackwell. pp. 135–136.

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