Synonyms 17β-(Cyclohexen-1-yloxy)-estra-1,3,5(10)-trien-3-ol propionate
CAS Number 13885-31-9
PubChem (CID) 20055348
ChemSpider 16736660
Chemical and physical data
Formula C27H36O3
Molar mass 408.57294 g/mol
3D model (Jmol) Interactive image

Orestrate (INN), also known as estradiol 3-propionate 17β-(1-cyclohexenyl) ether, is a synthetic, steroidal estrogen and estradiol ester that was never marketed.[1][2][3][4] It is the 3-propanoyl, 17-(1-cyclohexenyl) ether and ester of estradiol.[1][3]


  1. 1 2 J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 898, 905. ISBN 978-1-4757-2085-3.
  2. P. H. List; L. Hörhammer (12 March 2013). Chemikalien und Drogen Teil A: N-Q. Springer-Verlag. pp. 331–. ISBN 978-3-642-65035-2.
  3. 1 2 Edward B. Roche; Academy of Pharmaceutical Sciences. Medicinal Chemistry Section (1977). Design of biopharmaceutical properties through prodrugs and analogs: a symposium. The Academy. p. 7. ISBN 978-0-917330-16-2.
  4. Galletti, F.; Gardi, R. (1974). "Effect of two orally active estradiol derivatives on sulfobromphthalein retention in rats". Pharmacological Research Communications. 6 (2): 135–145. doi:10.1016/S0031-6989(74)80021-4. ISSN 0031-6989.

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