|Chemical and physical data|
|Molar mass||380.51978 g/mol|
|3D model (Jmol)||Interactive image|
Nilestriol (INN) (brand name Wei Ni An; developmental code name LY-49825), also known as nylestriol (USAN, BAN), is a synthetic, steroidal estrogen that was patented in 1971 and is marketed in China. It is the 3-cyclopentyl ether of ethinyl estriol, and is also known as ethinyl estriol cyclopentyl ether (EE3CPE). Nilestriol is a prodrug of ethinyl estriol, and is a more potent estrogen in comparison. It is described as a slowly-metabolized, long-acting estrogen and derivative of estriol. Nilestriol was assessed in combination with levonorgestrel for the potential treatment of postmenopausal osteoporosis, but this formulation ultimately was not marketed.
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