Estradiol butyrate benzoate

Estradiol butyrate benzoate
Clinical data
Routes of
CAS Number 63042-18-2
PubChem (CID) 67081
ChemSpider 60431
Chemical and physical data
Formula C29H34O4
Molar mass 446.57786 g/mol
3D model (Jmol) Interactive image

Estradiol butyrate benzoate, or estradiol 3-benzoate 17β-n-butyrate, also known as estra-1,3,5(10)-triene-3,17β-diol 3-benzoate 17β-n-butyrate, is a semisynthetic, steroidal estrogen and an estrogen ester – specifically, the 3-benzoate 17β-n-butyrate diester of estradiol – which was never marketed.[1][2] Under the tentative brand name Unimens, estradiol butyrate benzoate was studied in combination with the progestogen algestone acetophenide (dihydroxyprogesterone acetophenide) as a once-monthly combined injectable contraceptive (at doses of 10 mg and 150 mg, respectively).[1][2][3]

See also


  1. 1 2 Toppozada M (1977). "The clinical use of monthly injectable contraceptive preparations". Obstet Gynecol Surv. 32 (6): 335–47. PMID 865726.
  2. 1 2 Mokhtar K. Toppozada (1983), Monthly Injectable Contraceptives (PDF)
  3. Elsayed Saad Eldin Hafez (1980). Human reproduction: conception and contraception. Harper and Row. ISBN 978-0-06-141066-6.

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