Clinical data
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Routes of
ATC code ?? (WHO)
Legal status
Legal status
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Pharmacokinetic data
Bioavailability ?
Metabolism ?
Biological half-life ?
Excretion ?
CAS Number 77-32-7 N
PubChem (CID) 667509
DrugBank ? N
ChemSpider 580885 YesY
ECHA InfoCard 100.000.929
Chemical and physical data
Formula C8H12N2O2S
Molar mass 200.259
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

Thiobarbital is a drug which is a barbiturate derivative. It is the thiobarbiturate analogue of barbital.


Thiobarbital synthesis:[1][2]

It is of note that although the drug can be prepared by the above route (cf eg thialbarbital), rxn of barbital with phosphorus pentasulfide constitutes an alternative route to thiobarbital.


  1. Fischer, E.; Dilthey, A. (1904). "Ueber C-Dialkylbarbitursäuren und über die Ureïde der Dialkylessigsäuren". Justus Liebig's Annalen der Chemie. 335 (3): 334. doi:10.1002/jlac.19043350303.
  2. Carrington, H. C. (1944). "45. The action of phosphorus pentasulphide on barbituric acids". Journal of the Chemical Society (Resumed): 124. doi:10.1039/JR9440000124.

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