Combination of
Phenazone Analgesic
Chloral hydrate Sedative
Clinical data
MedlinePlus a601064
Routes of
ATC code N05CC04 (WHO)
Legal status
Legal status
CAS Number 480-30-8 YesY
PubChem (CID) 10188
DrugBank DB01495 YesY
ChemSpider 9776 YesY
UNII YYX637R279 YesY
KEGG D03785 YesY
ECHA InfoCard 100.006.861

Dichloralphenazone is a 1:2 mixture of antipyrine with chloral hydrate. In combination with paracetamol and isometheptene, it is the active ingredient of medications for migraine and vascular (tension) headaches, including Epidrin and Midrin. Performance impairments are common with this drug and caution is advised, for example when driving motor vehicles. Additional uses of dichloralphenazone include sedation for the treatment of short-term insomnia, although there are probably better drug choices for the treatment of insomnia.[1]

See also


  1. Hindmarch I; Parrott AC. (1980). "The effects of combined sedative and anxiolytic preparations on subjective aspects of sleep and objective measures of arousal and performance the morning following nocturnal medication. I: Acute doses.". Arzneimittelforschung. 30 (6): 1025–8. PMID 6106498.

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