Clinical data
ATC code none
Legal status
Legal status
CAS Number 2898-13-7 YesY
PubChem (CID) 17931
ChemSpider 16935 YesY
KEGG D05942 YesY
Chemical and physical data
Formula C16H13ClN2S
Molar mass 300.81 g/mol
3D model (Jmol) Interactive image

Sulazepam is a benzodiazepine derivative. It is the thioamide derivative of diazepam. It is metabolised into diazepam, desmethyldiazepam and oxydiazepam. It has sedative, muscle relaxant, hypnotic, anticonvulsant and anxiolytic properties like those of other benzodiazepines.[1][2] It was never marketed.


Sulazepam synthesis:[3] U.S. Patent 3,141,890

Treatment of diazepam with phosphorus pentasulfide produces the corresponding thionamide, sulazepam.

See also


  1. "sulazepam". 2003. Retrieved 29 December 2008.
  2. Golovenko NIa, Zin'kovskii VG (September 1976). "(title in Russian)" [Analysis of the structure of the components of the convulsive action of corazole following administration of sulazepam and its metabolites to mice]. Biull Eksp Biol Med (in Russian). 82 (9): 1078–1081. PMID 11012.
  3. Archer, G. A.; Sternbach, L. H. (1964). "Quinazolines and 1,4-Benzodiazepines. XVI.1Synthesis and Transformations of 5-Phenyl-1,4-benzodiazepine-2-thiones". The Journal of Organic Chemistry. 29: 231. doi:10.1021/jo01024a511.
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