Not to be confused with nitrazepam.
Legal status
Legal status
CAS Number 28910-99-8
PubChem (CID) 20317278
ChemSpider 15387105
Chemical and physical data
Formula C17H13N5O2
Molar mass 319.32 g·mol−1
3D model (Jmol) Interactive image

Nitrazolam is a benzodiazepine[1] that has been sold online as a designer drug.[2][3]

It is closely related to clonazolam, only differing by the removal of a chlorine group at the benzene ring.

Animal studies indicate that nitrazolam can be several times more potent than diazepam as an antagonist of electroshock-induced tonic-extensor convulsions.[4]

See also


  1. Jackson B. Hester, Jr (19 October 1976). "Patent US3987052 - 6-Phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepines". The Upjohn Company.
  2. "Nitrazolam". New Synthetic Drugs Database.
  3. Moosmann, Bjoern; Bisel, Philippe; Franz, Florian; Huppertz, Laura M.; Auwärter, Volker (2016). "Characterization and in vitro phase I microsomal metabolism of designer benzodiazepines – an update comprising adinazolam, cloniprazepam, fonazepam, 3-hydroxyphenazepam, metizolam, and nitrazolam". Journal of Mass Spectrometry. doi:10.1002/jms.3840. ISSN 1096-9888. PMID 27535017 via Wiley Online Library.
  4. Jackson B. Hester Jr.; Allan D. Rudzik; Bharat V. Kamdar (November 1971). "6-Phenyl-4H-s-triazolo[4,3-a] [1,4]benzodiazepines which have central nervous system depressant activity". Journal of Medicinal Chemistry. 14 (11): 1078–1081. doi:10.1021/jm00293a015. PMID 5165540.

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