Clinical data
ATC code None
CAS Number 406-90-6
PubChem (CID) 9844
ChemSpider 9461
ECHA InfoCard 100.006.344
Chemical and physical data
Formula C4H5F3O
Molar mass 126.077 g/mol
3D model (Jmol) Interactive image

Fluroxene (INN, USAN; brand name Fluoromar), or 2,2,2-trifluoroethyl vinyl ether, is a volatile, inhalational anesthetic, and was the first halogenated hydrocarbon anesthetic to be introduced.[1][2] It was synthesized in 1951, and was introduced for clinical use in 1954, but was voluntarily withdrawn from the market in 1974 due to its potential flammability and accumulating evidence that it could cause organ toxicity.[2][1][3] In any case, prior to being discontinued, it had largely been superseded by halothane.[4]

See also


  1. 1 2 Robert K. Stoelting; Simon C. Hillier (11 January 2012). Pharmacology and Physiology in Anesthetic Practice. Lippincott Williams & Wilkins. pp. 142–. ISBN 978-1-4511-6583-8.
  2. 1 2 Paul G Barash; Bruce F Cullen; Robert K Stoelting; Michael Cahalan; M Christine Stock (1 January 2011). Clinical Anesthesia. Lippincott Williams & Wilkins. pp. 113–. ISBN 978-1-4511-2297-8.
  3. Monte Lichtiger; Frank Moya (1 January 1978). Introduction to the practice of anesthesia. Medical Dept., Harper & Row. ISBN 978-0-06-141534-0.
  4. Acta anaesthesiologica Belgica. Acta Medica Belgica. 1974.

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