IUPAC name
Other names
77-66-7 YesY
3D model (Jmol) Interactive image
Interactive image
ChEMBL ChEMBL2104673
ChemSpider 6244 YesY
ECHA InfoCard 100.000.953
EC Number 201-047-1
KEGG D07059 YesY
MeSH acecarbromal
PubChem 6489
Molar mass 279.13 g·mol−1
Legal status
  • ℞ (Prescription only)
Related compounds
Related compounds
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Acecarbromal (INN) (brand names Sedamyl, Abasin, Carbased, Paxarel, Sedacetyl, numerous others), also known as acetylcarbromal and acetyladalin, is a hypnotic and sedative drug of the ureide (acylurea) group discovered by Bayer in 1917[1] that was formerly marketed in the United States and Europe.[2][3] It is also used in combination with extract of quebracho and vitamin E as a treatment for erectile dysfunction under the brand name Afrodor in Europe.[4][5][6] Acecarbromal is structurally related to the barbiturates, which are basically cyclized ureas.[7] Prolonged use is not recommended as it can cause bromine poisoning.[7]

See also


  1. DE Patent 327129
  2. J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 2–. ISBN 978-1-4757-2085-3.
  3. Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 4–. ISBN 978-3-88763-075-1.
  4. Muller (19 June 1998). European Drug Index: European Drug Registrations, Fourth Edition. CRC Press. pp. 36–. ISBN 978-3-7692-2114-5.
  5. Baumbusch, F; Papp, GK; Kopa, ZS (1995). "Treatment for potency problems with Afrodor 2000". Acta chirurgica Hungarica. 35 (1–2): 87–92. PMID 8659243.
  6. Sperling, H; Lümmen, G; Luboldt, HJ; Rübben, H (1999). "Secondary erectile dysfunction. Is oral medication in the diagnostic phase indicated?". Der Urologe. Ausg. A. 38 (1): 56–9. doi:10.1007/s001200050246. PMID 10081103.
  7. 1 2 David A. Williams; William O. Foye; Thomas L. Lemke (January 2002). Foye's Principles of Medicinal Chemistry. Lippincott Williams & Wilkins. pp. 380–. ISBN 978-0-683-30737-5.

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