Frizzled-10 is a protein that in humans is encoded by the FZD10 gene. FZD10 has also been designated as CD350 (cluster of differentiation 350).
This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.