Glycoprotein Ib (GPIb), also known as CD42, is a component of the GPIb-V-IX complex on platelets. The GPIb-V-IX complex binds von Willebrand factor, allowing platelet adhesion and platelet plug formation at sites of vascular injury.
Autoantibodies against Ib/IX can be produced in immune thrombocytopenic purpura.
It complexes with Glycoprotein IX.
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