Prokineticin receptor

prokineticin receptor 1
Symbol PROKR1
Alt. symbols GPR73
Entrez 10887
HUGO 4524
OMIM 607122
RefSeq NM_138964
UniProt Q8TCW9
Other data
Locus Chr. 2 p14
prokineticin receptor 2
Symbol PROKR2
Alt. symbols GPR73L1
Entrez 128674
HUGO 15836
OMIM 607123
RefSeq NM_144773
UniProt Q8NFJ6
Other data
Locus Chr. 20 p12.3

The prokineticin receptor is a G protein-coupled receptor which binds the peptide hormone prokineticin. There are two variants each encoded by a different gene (PROKR1, PROKR2).[1] These receptors mediate gastrointestinal smooth muscle contraction and angiogenesis.


  1. Lin DC, Bullock CM, Ehlert FJ, Chen JL, Tian H, Zhou QY (2002). "Identification and molecular characterization of two closely related G protein-coupled receptors activated by prokineticins/endocrine gland vascular endothelial growth factor". J. Biol. Chem. 277 (22): 19276–80. doi:10.1074/jbc.M202139200. PMID 11886876.

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