ING2

ING2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases ING2, ING1L, p33inhibitor of growth family member 2
External IDs MGI: 1916510 HomoloGene: 20388 GeneCards: ING2
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

3622

69260

Ensembl

ENSG00000168556

ENSMUSG00000063049

UniProt

Q9H160

Q9ESK4

RefSeq (mRNA)

NM_001291959
NM_001564

NM_023503

RefSeq (protein)

NP_001278888.1
NP_001555.1

NP_075992.2

Location (UCSC) Chr 4: 183.5 – 183.51 Mb Chr 8: 47.67 – 47.68 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Inhibitor of growth protein 2 is a protein that in humans is encoded by the ING2 gene.[3][4]

Function

This gene is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis.[4]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Shimada Y, Saito A, Suzuki M, Takahashi E, Horie M (Mar 1999). "Cloning of a novel gene (ING1L) homologous to ING1, a candidate tumor suppressor". Cytogenetics and Cell Genetics. 83 (3-4): 232–5. doi:10.1159/000015188. PMID 10072587.
  4. 1 2 "Entrez Gene: ING2 inhibitor of growth family, member 2".

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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