Ethylene-responsive element binding protein

Ethylene-responsive element binding protein

NMR structure of the GCC-BOX binding domain of EREBP (green) complexed with DNA (brown) based on the PDB: 1GCC coordinates.
Symbol EREBP
Entrez 827464
UniProt O80337
AP2 domain

Structure of the GCC-box binding domain.[1]
Symbol AP2
Pfam PF00847
Pfam clan CL0081
InterPro IPR001471
SCOP 3gcc

Ethylene-responsive element binding protein (EREBP) is a homeobox gene from Arabidopsis thaliana and other plants which encodes a transcription factor.[2] EREBP is responsible in part for mediating the response in plants to the plant hormone ethylene.[3][4]


  1. Allen MD, Yamasaki K, Ohme-Takagi M, Tateno M, Suzuki M (September 1998). "A novel mode of DNA recognition by a beta-sheet revealed by the solution structure of the GCC-box binding domain in complex with DNA". EMBO J. 17 (18): 5484–96. doi:10.1093/emboj/17.18.5484. PMC 1170874Freely accessible. PMID 9736626.
  2. Riechmann JL, Meyerowitz EM (June 1998). "The AP2/EREBP family of plant transcription factors". Biol. Chem. 379 (6): 633–46. doi:10.1515/bchm.1998.379.6.633. PMID 9687012.
  3. Ohme-Takagi M, Shinshi H (February 1995). "Ethylene-inducible DNA binding proteins that interact with an ethylene-responsive element". Plant Cell. 7 (2): 173–82. doi:10.1105/tpc.7.2.173. PMC 160773Freely accessible. PMID 7756828.
  4. Büttner M, Singh KB (May 1997). "Arabidopsis thaliana ethylene-responsive element binding protein (AtEBP), an ethylene-inducible, GCC box DNA-binding protein interacts with an ocs element binding protein". Proc. Natl. Acad. Sci. U.S.A. 94 (11): 5961–6. doi:10.1073/pnas.94.11.5961. PMC 20889Freely accessible. PMID 9159183.

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