TOX high mobility group box family member 2
Symbol TOX2
Alt. symbols C20orf100, GCX-1
Entrez 84969
HUGO 16095
OMIM 611163
RefSeq NM_001098796
UniProt Q96NM4
Other data
Locus Chr. 20 q13.12

TOX high mobility group box family member 2, also known as TOX2, is a human gene.[1][2]

The protein encoded by this gene is a member of a subfamily of transcription factors that also includes TOX, TOX3, and TOX4 that share almost identical HMG-box DNA-binding domains which function to modify chromatin structure.[3]


  1. "Entrez Gene: TOX high mobility group box family member 2".
  2. Kajitani T, Mizutani T, Yamada K, Yazawa T, Sekiguchi T, Yoshino M, Kawata H, Miyamoto K (May 2004). "Cloning and characterization of granulosa cell high-mobility group (HMG)-box protein-1, a novel HMG-box transcriptional regulator strongly expressed in rat ovarian granulosa cells". Endocrinology. 145 (5): 2307–18. doi:10.1210/en.2003-1343. PMID 14764631.
  3. O'Flaherty E, Kaye J (April 2003). "TOX defines a conserved subfamily of HMG-box proteins". BMC Genomics. 4: 13. doi:10.1186/1471-2164-4-13. PMC 155677Freely accessible. PMID 12697058.

This article is issued from Wikipedia - version of the 6/3/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.