Clinical data
Routes of
ATC code none
Legal status
Legal status
CAS Number 15066-09-8
113997-84-5 (R isomer)
113997-85-6 (S isomer)
PubChem (CID) 14083213
ChemSpider 23128298 YesY
Chemical and physical data
Formula C11H14N2O
Molar mass 190.25 g·mol−1
3D model (Jmol) Interactive image
Melting point 125–126 °C (257–259 °F) [1]

4-Hydroxy-α-methyltryptamine (4-HO-αMT) is a psychedelic drug of the tryptamine class. It is a close structural analogue of α-methyltryptamine (αMT) and produces similar effects to it, but with exacerbated side effects similarly to 5-MeO-αMT. Alexander Shulgin describes 4-HO-αMT briefly in his book TiHKAL:[2]

The 4-hydroxy analogue of αMT has been looked at in human subjects. It is reported to be markedly visual in its effects, with some subjects reporting dizziness and a depressed feeling. There were, however, several toxic signs at doses of 15 to 20 milligrams orally, including abdominal pain, tachycardia, increased blood pressure and, with several people, headache and diarrhea.

See also


  1. Troxler, F.; Seemann, F.; Hofmann, A. (1959). "Abwandlungsprodukte von Psilocybin und Psilocin. 2. Mitteilung über synthetische Indolverbindungen". Helvetica Chimica Acta (in German). 42 (6): 2073–2103. doi:10.1002/hlca.19590420638.
  2. "Erowid Online Books : "TIHKAL" - #48 a-MT".
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