CAS Number 36288-76-3 N
PubChem (CID) 71360804
ChemSpider 29358411
Chemical and physical data
Formula C16H24N2O
Molar mass 260.37 g/mol
3D model (Jmol) Interactive image

5-HO-DiPT (5-hydroxy-N,N-di-iso-propyltryptamine) is a tryptamine derivative which acts as a serotonin receptor agonist. It is primarily known as a metabolite of the better known psychoactive drug 5-MeO-DiPT,[1] but 5-HO-DiPT has also rarely been encountered as a designer drug in its own right.[2] Tests in vitro show 5-HO-DiPT to have high 5-HT2A affinity and good selectivity over 5-HT1A,[3] while being more lipophilic than the related drug bufotenine (5-HO-DMT), which produces mainly peripheral effects.

See also


  1. Yu, A. M. (2008). "Indolealkylamines: Biotransformations and Potential Drug–Drug Interactions". The AAPS Journal. 10 (2): 242–253. doi:10.1208/s12248-008-9028-5. PMC 2751378Freely accessible. PMID 18454322.
  2. Brandt, S. D.; Martins, C. U. P. B. (2010). "Analytical methods for psychoactive N,N-dialkylated tryptamines". TrAC Trends in Analytical Chemistry. 29 (8): 858. doi:10.1016/j.trac.2010.04.008.
  3. McKenna, D. J.; Repke, D. B.; Lo, L.; Peroutka, S. J. (1990). "Differential interactions of indolealkylamines with 5-hydroxytryptamine receptor subtypes". Neuropharmacology. 29 (3): 193–198. doi:10.1016/0028-3908(90)90001-8. PMID 2139186.

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