CAS Number 127507-01-1 N 77872-40-3 (hydrochloride)
PubChem (CID) 21786580
ChemSpider 10513070
Chemical and physical data
Formula C18H28N2O
Molar mass 288.43 g/mol
3D model (Jmol) Interactive image

4-HO-DSBT (4-hydroxy-N,N-di-sec-butyltryptamine) is a tryptamine derivative which acts as a serotonin receptor agonist. It was first made by Alexander Shulgin and is mentioned in his book TiHKAL, but was never tested by him.[1] However it has subsequently been tested in vitro and unlike the n-butyl and isobutyl isomers which are much weaker, the s-butyl derivative retains reasonable potency, with a similar 5-HT2A receptor affinity to MiPT but better selectivity over the 5-HT1A and 5-HT2B subtypes.[2]

See also


  1. 4-HO-DBT TiHKAL entry
  2. McKenna, D. J.; Repke, D. B.; Lo, L.; Peroutka, S. J. (1990). "Differential interactions of indolealkylamines with 5-hydroxytryptamine receptor subtypes". Neuropharmacology. 29 (3): 193–198. doi:10.1016/0028-3908(90)90001-8. PMID 2139186.

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