Trifluperidol

Trifluperidol
Clinical data
AHFS/Drugs.com International Drug Names
Routes of
administration
Oral
ATC code N05AD02 (WHO)
Identifiers
CAS Number 749-13-3 N
PubChem (CID) 5567
ChemSpider 5366 YesY
UNII R8869Q7R8I YesY
ChEMBL CHEMBL15023 YesY
Chemical and physical data
Formula C22H23F4NO2
Molar mass 409.417 g/mol
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

Trifluperidol is a typical antipsychotic of the butyrophenone chemical class. It has general properties similar to those of haloperidol, but is considerably more potent by weight, and causes relatively more severe side effects, especially tardive dyskinesia and other extrapyramidal effects. It is used in the treatment of psychoses including mania and schizophrenia. It was discovered at Janssen Pharmaceutica in 1959.

Synthesis

Trifluperidol Synthesis: P. Janssen, J. Adriaan, GB 895309  (1962), U.S. Patent 3,438,991 (1969).

References

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