13712-80-6 freebase |
13518-76-8 hydrochloride salt
|Chemical and physical data|
|Molar mass||202.295 g/mol|
|3D model (Jmol)||Interactive image|
7-Methyl-α-ethyltryptamine (7-Me-αET) is a tryptamine derivative related to α-ethyltryptamine (αET). It was discovered by a team at Upjohn in the early 1960s. It has similar pharmacological effects to αET, but is both 3-4 times more potent as a serotonin releasing agent, and 10 times more potent as a monoamine oxidase inhibitor, making it potentially hazardous as this pharmacological profile is shared with drugs such as PMA and 4-MTA, which are known to be dangerous in humans when used at high doses.
- U.S. Patent 3,296,072
- Hester, J. B.; Greig, M. E.; Anthony, W. C.; Heinzelman, R. V.; Szmuszkovicz, J. (1964). "Enzyme Inhibitory Activity of 3-(2-Aminobutyl)indole Derivatives". Journal of Medicinal Chemistry. 7 (3): 274. doi:10.1021/jm00333a006.
- Burningham RA; Arimura GK; Yunis AA (July 1966). "Effect of Monase and related compounds on uptake of 5-hydroxytryptamine by platelets". Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine. 122 (3): 711–4. doi:10.3181/00379727-122-31233. PMID 5918937.