Delmadinone acetate

Delmadinone acetate
Clinical data
ATCvet code QG03DX91 (WHO)
CAS Number 13698-49-2
PubChem (CID) 10135765
ChemSpider 8311278
Chemical and physical data
Formula C23H27ClO4
Molar mass 402.911 g/mol
3D model (Jmol) Interactive image

Delmadinone acetate (INN, USAN, BAN) (brand names Delmate, Estrex, Tardak, Tardastren, Tardastrex, Vetadinon, Zenadrex), sometimes abbreviated as DMA, and also known as 1,6-bisdehydro-6-chloro-17α-acetoxyprogesterone, is a steroidal progestin with antigonadotropic (and hence, antiandrogenic and antiestrogenic) properties which is used to treat androgen-associated conditions in veterinary medicine.[1][2][3] It must be used with care as it has the potential to cause adrenal insufficiency via inhibition of adrenocorticotropic hormone (ACTH) secretion from the pituitary gland.[4]

See also


  1. F.. Macdonald (1997). Dictionary of Pharmacological Agents. CRC Press. p. 579. ISBN 978-0-412-46630-4. Retrieved 30 May 2012.
  2. Index Nominum 2000: International Drug Directory. Taylor & Francis US. 2000. p. 298. ISBN 978-3-88763-075-1. Retrieved 30 May 2012.
  3. Ian Morton; Judith M. Hall (1999). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer. p. 92. ISBN 978-0-7514-0499-9. Retrieved 30 May 2012.
  4. Court EA, Watson AD, Church DB, Emslie DR (August 1998). "Effects of delmadinone acetate on pituitary-adrenal function, glucose tolerance and growth hormone in male dogs". Australian Veterinary Journal. 76 (8): 555–60. doi:10.1111/j.1751-0813.1998.tb10216.x. PMID 9741725.

This article is issued from Wikipedia - version of the 10/10/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.