Pentagestrone acetate

Pentagestrone acetate
Clinical data
Trade names Gestovis, Gestovister
CAS Number 1178-60-5
PubChem (CID) 10321047
ChemSpider 8496511
UNII 3Y30374T6H
Chemical and physical data
Formula C28H40O4
Molar mass 440.6148 g/mol
3D model (Jmol) Interactive image

Pentagestrone acetate (brand names Gestovis, Gestovister), also known as 17α-acetoxyprogesterone 3-cyclopentyl enol ether, is a steroidal progestin of the 17α-hydroxyprogesterone group that was described in the literature in 1960 and introduced by Vister in Italy in 1961.[1][2][3] It is the 3-cyclopentyl enol ether of 17α-hydroxyprogesterone acetate.[4] Pentagestrone acetate, along with quingestrone (the 3-cyclopentyl enol ether of progesterone), is said to have very similar properties to those of dydrogesterone, a pure progestogen and close analogue of progesterone.[5]

See also


  1. J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 943–. ISBN 978-1-4757-2085-3.
  2. Drugs Available Abroad. Gale Research. 1991. ISBN 978-0-8103-7177-4.
  3. P. H. List; L. Hörhammer (12 March 2013). Chemikalien und Drogen Teil A: N-Q. Springer-Verlag. pp. 508–. ISBN 978-3-642-65035-2.
  4. Camille Georges Wermuth (2 May 2011). The Practice of Medicinal Chemistry. Academic Press. pp. 731–. ISBN 978-0-08-056877-5.
  5. Revue générale des sciences pures et appliquées et bulletin de l'Association française pour l'avancement des sciences. Société d'édition d'enseignement supérieur. 1964. [[...] Ercoli (1960) developed cyclopentyl enol ethers of progesterone (Luteovis) and acetoxy progesterone (Gestovis), which have almost exactly the same properties as dydrogesterone.]

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