Clinical data
AHFS/ International Drug Names
ATC code M01AE17 (WHO) M02AA27 (WHO)
Legal status
Legal status
  • UK: POM (Prescription only)
CAS Number 22161-81-5 N
PubChem (CID) 667550
ChemSpider 580922 N
UNII 6KD9E78X68 YesY
KEGG D07269 YesY
ECHA InfoCard 100.118.639
Chemical and physical data
Formula C16H14O3
Molar mass 254.28056 g/mol
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

Dexketoprofen is a non-steroidal anti-inflammatory drug. It is manufactured by Menarini, under the tradename Keral. It is available in the UK, as dexketoprofen trometamol, as a prescription-only drug and in Latin America as Enantyum, produced by Menarini. Also, in Italy and Spain it is available as an over-the-counter drug (OTC) under the tradename respectively Enantyum, Ketesgel. In Latvia, Lithuania and Estonia it is available as over-the-counter drug (OTC) under tradename Dolmen.[1] In Mexico it is available in tablet form as "Stadium" made by Menarini. It is the dextrorotatory stereoisomer of ketoprofen.[2]

Medical uses

Short-term treatment of mild to moderate pain, including dysmenorrhoea.

Side effects

It may cause dizziness and so may affect the ability to drive.


Dexketoprofen belongs to a class of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It works by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is involved in the production of chemicals in the body called prostaglandins. Prostaglandins are produced in response to injury or certain diseases and would otherwise go on to cause swelling, inflammation and pain. By blocking cyclo-oxygenase, dexketoprofen prevents the production of prostaglandins and therefore reduces inflammation and pain. Along with Peripheral analgesic action it possesses central analgesic action.


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