|AHFS/Drugs.com||International Drug Names|
|Oral, IM, IV|
|ATC code||N02AX05 (WHO)|
|Metabolism||The peak analgesic effect is seen within 30–60 minutes and lasts about 3–4 hours.|
|Biological half-life||Half-Life (1.4–4 hours).|
|Excretion||The drug is rapidly metabolised to the glucuronide, and mostly excreted in the urine.|
|Chemical and physical data|
|Molar mass||233.34922 g/mol|
|3D model (Jmol)||Interactive image|
|(what is this?)|
A partial µ-opioid receptor agonist, its mixed agonist/antagonist activity affords it a lower risk of dependence and abuse than full µ agonists like morphine. Meptazinol exhibits not only a short onset of action, but also a shorter duration of action relative to other opioids such as morphine, pentazocine, or buprenorphine.
- US patent 4197239, Cavalla JF, Shepherd RG, White AC, "Hexahydroazepine, Piperidine and Pyrrolidine Derivatives", issued 1980-04-08, assigned to Wyeth
- Holmes B, Ward A (1985). "Meptazinol. A Review of its Pharmacodynamic and Pharmacokinetic Properties and Therapeutic Efficacy". Drugs. 30 (4): 285–312. doi:10.2165/00003495-198530040-00001. PMID 2998723.