Bucetin

Bucetin
Clinical data
ATC code N02BE04 (WHO)
Identifiers
CAS Number 1083-57-4 YesY
PubChem (CID) 14130
ChemSpider 13507
UNII 6M7CVQ8PF8 YesY
ChEMBL CHEMBL1697856
Chemical and physical data
Formula C12H17NO3
Molar mass 223.268 g/mol
3D model (Jmol) Interactive image

Bucetin (INN, BAN) is an analgesic and antipyretic that is no longer marketed.[1][2] Chemically, it is similar to phenacetin with which it shares the risk of carcinogenesis.[3] Bucetin was withdrawn from use in 1986 due to renal toxicity.[4]

See also

References

  1. J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 184–. ISBN 978-1-4757-2085-3.
  2. "WHOCC - ATC/DDD Index". WHO Collaborating Centre for Drug Statistics Methodology. December 19, 2013.
  3. Togei, K; Sano, N; Maeda, T; Shibata, M; Otsuka, H (1987). "Carcinogenicity of bucetin in (C57BL/6 X C3H)F1 mice". Journal of the National Cancer Institute. 79 (5): 1151–8. doi:10.1093/jnci/79.5.1151. PMID 3479641.
  4. Fung, M.; Thornton, A.; Mybeck, K.; Wu, J. H.-h.; Hornbuckle, K.; Muniz, E. (2001). "Evaluation of the Characteristics of Safety Withdrawal of Prescription Drugs from Worldwide Pharmaceutical Markets-1960 to 1999". Drug Information Journal. 35: 293–317. doi:10.1177/009286150103500134.
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