Clinical data
AHFS/ International Drug Names
ATC code M01AB14 (WHO)
Pharmacokinetic data
Metabolism Hepatic. Undergoes enterohepatic recirculation
Synonyms 3-[4-[2-[2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetyl]oxyethyl]piperazin-1-yl]propyl 4-(benzoylamino)-5-(dipropylamino)-5-oxopentanoate
CAS Number 57132-53-3 59209-40-4
PubChem (CID) 4921
ChemSpider 4752 YesY
UNII FV919079LU YesY
Chemical and physical data
Formula C46H58ClN5O8
Molar mass 844.43442 g/mol
3D model (Jmol) Interactive image

Proglumetacin (usually as the maleate salt, trade names Afloxan, Protaxon and Proxil) is a non-steroidal anti-inflammatory drug. It is metabolized in the body to indometacin and proglumide,[1] a drug with antisecretory effects that helps prevent injury to the stomach lining.


  1. Setnikar I, Arigoni R, Chisté R, Makovec F, Revel L (1987). "Plasma levels of proglumetacin and its metabolites after intravenous or oral administration in the dog". Arzneimittel-Forschung. 37 (6): 698–702. PMID 3663267.

This article is issued from Wikipedia - version of the 6/8/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.