Tilmacoxib

Tilmacoxib
Pharmacokinetic data
Bioavailability solution (64–88%) compared with capsule (22–40%).
Identifiers
PubChem (CID) 159271
ChemSpider 140082
UNII G6VI5P84SX
ChEBI CHEBI:73041 YesY
ChEMBL CHEMBL34913
Chemical and physical data
Formula C16H19FN2O3S
Molar mass 338.397 g/mol
3D model (Jmol) Interactive image

Tilmacoxib or JTE-522 is a COX-2 inhibitor and is an effective chemopreventive agent against rat experimental liver fibrosis.[1]

See also

References

  1. Yamamoto, H., Kondo, M., Nakamori, S., Nagano, H., Wakasa, K., Sugita, Y., Chang-De, J., Kobayashi, S., Damdinsuren, B., Dono, K., Umeshita, K., Sekimoto, M., Sakon, M., Matsuura, N., Monden, M. (2003). "JTE-522, a cyclooxygenase-2 inhibitor, is an effective chemopreventive agent against rat experimental liver fibrosis1". Gastroenterology. 125 (2): 556–571. doi:10.1016/s0016-5085(03)00904-1. PMID 12891558.
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