Combination of
Clofexamide Antidepressant
Phenylbutazone Non-steroidal anti-inflammatory drug
Clinical data
Trade names Perclusone
Routes of
Oral, rectal, topical
ATC code M02AA03 (WHO) M01AA05 (WHO)
Legal status
Legal status
  • Discontinued
CAS Number 17449-96-6 N
PubChem (CID) 6433695
ChemSpider 4938775 YesY
 NYesY (what is this?)  (verify)

Clofezone (trade name Perclusone) is a drug that was used to treat joint and muscular pain, but is not marketed any more. It is a combination of clofexamide, an antidepressant, and phenylbutazone, a non-steroidal anti-inflammatory drug (NSAID).[1][2]


  1. Berger, Artur; Wachter, Helmut, eds. (1998). Hunnius Pharmazeutisches Wörterbuch (in German) (8 ed.). Walter de Gruyter Verlag. p. 343. ISBN 3-11-015793-4.
  2. Reinicke, C.; Helbing, M.; Klingenfeld, U.; Lasaroff, I.; Wessel, G. (1984). "Comparative studies on the bioavailability of various drug forms of phenylbutazone and clofezone (Perclusone)". Die Pharmazie. 39 (12): 824–827. PMID 6241720.

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