In enzymology, a [RNA-polymerase]-subunit kinase (EC 126.96.36.199) is an enzyme that catalyzes the chemical reaction
- ATP + [DNA-directed RNA polymerase] ADP + phospho-[DNA-directed RNA polymerase]
Thus, the two substrates of this enzyme are ATP and DNA-directed RNA polymerase, whereas its two products are ADP and [[phospho-[DNA-directed RNA polymerase]]].
This enzyme belongs to the family of transferases, specifically those transferring a phosphate group to the sidechain oxygen atom of serine or threonine residues in proteins (protein-serine/threonine kinases). The systematic name of this enzyme class is ATP:[DNA-directed RNA polymerase] phosphotransferase. Other names in common use include CTD kinase, and STK9.