EM of a plasmavirus
Virus classification
Group: Group I (dsDNA)
Family: Plasmaviridae
  • Plasmavirus

Plasmaviridae is a family of bacteria-infecting viruses. Acholeplasma species serve as natural hosts. There are currently only one genus (Plasmavirus), and one species in this family: the type species Acholeplasma phage L2. [1][2] All species known in this family have been isolated from species in the class Mollicutes.

This family is poorly studied and little is known about these viruses.


The family has one genus, Plasmavirus, which has one recognized member. There are five tentative members of Plasmavirus:

Group: dsDNA



The genome is condensed, nonsegmented and consists of a single molecule of circular, supercoiled double-stranded DNA, 12 kilobase pairs in length. The genome has a rather high G-C content of ~32%.[3] The genome has 14 open reading frames,[1] and encodes at least 15 proteins, of which at least four are structural proteins embedded in the membrane.


Virions have an envelope, a nucleoprotein complex, and a capsid, with spherical to pleomorphic and head-tail geometries.[1] They are 50–125 nm in diameter with a baggy or loose membrane.

Genus Structure Symmetry Capsid Genomic Arrangement Genomic Segmentation
PlasmavirusSpherical PleomorphicEnvelopedCircularMonopartite

Life Cycle

Viral replication is cytoplasmic. DNA-templated transcription is the method of transcription. The virus exits the host cell by budding. Acholeplasma species serve as the natural host.[1]

Genus Host Details Tissue Tropism Entry Details Release Details Replication Site Assembly Site Transmission
PlasmavirusMycoplasma bacteria: Acholeplasma sp.NoneUnknownUnknownUnknownCytoplasmUnknown


A productive infectious cycle begins before a lysogenic cycle establishes the virus in the infected bacteria. After initial infection of the viral genome the virus may become latent within the host. Lysogeny involves integration into the host chromosome.


  1. 1 2 3 4 "Viral Zone". ExPASy. Retrieved 15 June 2015.
  2. 1 2 ICTV. "Virus Taxonomy: 2014 Release". Retrieved 15 June 2015.
  3. Büchen-Osmond, C. (Ed) (2003). 00.053. Plasmaviridae. In: ICTVdB—The Universal Virus Database, version 3. Büchen-Osmond, C. (Ed), ICTVdB Management, The Earth Institute and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.
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