Clinical data
ATC code none
Legal status
Legal status
  • Uncontrolled
CAS Number 6053-02-7 N
PubChem (CID) 151398
ChemSpider 133430 YesY
UNII 28C0I29E70 N
KEGG C06224 YesY
Chemical and physical data
Formula C8H8O2
Molar mass 136.15 g/mol
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

3,4-Dihydroxystyrene (DHS) is a centrally-acting inhibitor of the enzyme phenylalanine hydroxylase (PH).[1] It is likely that DHS and other PH inhibitors will never have clinical applications on account of their capacity for inducing hyperphenylalaninemia and phenylketonuria.

See also


  1. Koizumi S; Matsushima Y; Nagatsu T; Iinuma H; Takeuchi T; Umezawa H (September 1984). "3,4-dihydroxystyrene, a novel microbial inhibitor for phenylalanine hydroxylase and other pteridine-dependent monooxygenases". Biochimica et Biophysica Acta. 789 (2): 111–8. doi:10.1016/0167-4838(84)90194-8. PMID 6148105.

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