Clinical data
Routes of
ATC code none
Legal status
Legal status
  • Uncontrolled
PubChem (CID) 18687754
ChemSpider 13701383 YesY
Chemical and physical data
Formula C14H8F4O4S
Molar mass 348.27 g/mol
3D model (Jmol) Interactive image

CX157 (proposed trade name TriRima, formerly Tyrima) is a selective and reversible inhibitor of MAO-A (RIMA).[1] As of 2007 it was in phase II clinical trials for the treatment of depression.[2] In 2013, it was discontinued for both depression and anxiety.


  1. Fielding R, Mielach F, Free J, Pande A (2007). Pharmacokinetics and oral bioavailability of CX157, a reversible selective MAO-A inhibitor, in primates (PDF). 2007 AAPS Annual Meeting & Exposition. Retrieved 2009-06-14.
  2. Clinical trial number NCT00739908 at

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