Lipid metabolism is the synthesis and degradation of lipids in cells.
Lipid metabolism is the break down or storage of fats for energy; these fats are obtained from consuming food and absorbing them or they are synthesized by an animal's liver. Lipid metabolism does exist in plants, though the processes differ in some ways when compared to animals. Lipogenesis is the process of synthesizing these fats. Lipid metabolism often begins with hydrolysis, which occurs when a chemical breaks down as a reaction to coming in contact with water. Since lipids (fats) are hydrophobic, hydrolysis in lipid metabolism occurs in the cytoplasm which ends up creating glycerol and fatty acids. Due to the hydrophobic nature of lipids they require special transport proteins known as lipoproteins, which are hydrophilic. Lipoproteins are categorized by their density levels. The varying densities between the types of lipoproteins are characteristic to what type of fats they transport. A number of these lipoproteins are synthesized in the liver, but not all of them originate from this organ.
Lipid Metabolism Disorders are illnesses where trouble occurs in breaking down or synthesizing fats (or fat-like substances). A good deal of the time these disorders are hereditary, meaning it's a condition that is passed along from parent to child through their genes. Gaucher's Disease (Type I, Type II, and Type III), Neimann-Pick Disease, Tay-sachs Disease, and Fabry's Disease are all diseases where those afflicted can have a disorder of their body's lipid metabolism. Rarer diseases concerning a disorder of the lipid metabolism are Sitosterolemia, Wolman's Disease, Refsum's Disease, and Cerebrotendinous Xanthomatosis.
The types of lipids involved in Lipid Metabolism include:
- Bile salts
- Ketone bodies
- Fatty acids - see also fatty acid metabolism
- Steroid - see also steroidogenesis
- Triacylglycerols (fats) - see also lipolysis and lipogenesis
- Lipid metabolism at the US National Library of Medicine Medical Subject Headings (MeSH)
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