Lycopene epsilon-cyclase

Lycopene epsilon-cyclase
Identifiers
EC number 5.5.1.18
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Lycopene epsilon-cyclase (EC 5.5.1.18, CrtL-e, LCYe) is an enzyme with systematic name carotenoid psi-end group lyase (decyclizing).[1][2] This enzyme catalyses the following chemical reaction

carotenoid psi-end group carotenoid epsilon-end group

The carotenoid lycopene has the psi-end group at both ends.

References

  1. Cunningham, F.X.; Jr.; Gantt, E. (2001). "One ring or two? Determination of ring number in carotenoids by lycopene ε-cyclases". Proc. Natl. Acad. Sci. USA. 98: 2905–2910. doi:10.1073/pnas.051618398. PMC 30238Freely accessible. PMID 11226339.
  2. Stickforth, P.; Steiger, S.; Hess, W.R.; Sandmann, G. (2003). "A novel type of lycopene ε-cyclase in the marine cyanobacterium Prochlorococcus marinus MED4". Arch. Microbiol. 179 (6): 409–415. doi:10.1007/s00203-003-0545-4. PMID 12712234.
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