Lycopene beta-cyclase
| Lycopene beta-cyclase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 5.5.1.19 | ||||||||
| CAS number | 220801-82-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Lycopene beta-cyclase (EC 5.5.1.19, CrtL, CrtL-b, CrtY) is an enzyme with systematic name carotenoid beta-end group lyase (decyclizing).[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction
- carotenoid psi-end group carotenoid beta-end group
This enzyme requires NAD(P)H.
References
- ↑ Cunningham, F.X. Jr.; Chamovitz, D.; Misawa, N.; Gantt, E.; Hirschberg, J. (1993). "Cloning and functional expression in Escherichia coli of a cyanobacterial gene for lycopene cyclase, the enzyme that catalyzes the biosynthesis of β-carotene". FEBS Lett. 328: 130–138. doi:10.1016/0014-5793(93)80980-9. PMID 8344419.
- ↑ Cunningham, F.X.; Jr.; Sun, Z.; Chamovitz, D.; Hirschberg, J.; Gantt, E. (1994). "Molecular structure and enzymatic function of lycopene cyclase from the cyanobacterium Synechococcus sp strain PCC7942". Plant Cell. 6: 1107–1121. doi:10.1105/tpc.6.8.1107. JSTOR 3869889. PMID 7919981.
- ↑ Hugueney, P.; Badillo, A.; Chen, H.C.; Klein, A.; Hirschberg, J.; Camara, B.; Kuntz, M. (1995). "Metabolism of cyclic carotenoids: a model for the alteration of this biosynthetic pathway in Capsicum annuum chromoplasts". Plant J. 8: 417–424. doi:10.1046/j.1365-313x.1995.08030417.x. PMID 7550379.
- ↑ Pecker, I.; Gabbay, R.; Cunningham, F.X. Jr.; Hirschberg, J. (1996). "Cloning and characterization of the cDNA for lycopene β-cyclase from tomato reveals decrease in its expression during fruit ripening". Plant Mol. Biol. 30: 807–819. doi:10.1007/bf00019013. PMID 8624411.
- ↑ Hornero-Mendez, D.; Britton, G. (2002). "Involvement of NADPH in the cyclization reaction of carotenoid biosynthesis". FEBS Lett. 515: 133–136. doi:10.1016/s0014-5793(02)02453-5. PMID 11943208.
- ↑ Maresca, J.A.; Graham, J.E.; Wu, M.; Eisen, J.A.; Bryant, D.A. (2007). "Identification of a fourth family of lycopene cyclases in photosynthetic bacteria". Proc. Natl. Acad. Sci. USA. 104: 11784–11789. doi:10.1073/pnas.0702984104. PMID 17606904.
External links
- Lycopene beta-cyclase at the US National Library of Medicine Medical Subject Headings (MeSH)
This article is issued from Wikipedia - version of the 8/10/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.