Ribonuclease T2

Not to be confused with ribonuclease T or ribonuclease T1.
Ribonuclease T2
Identifiers
EC number 3.1.27.1
CAS number 37278-25-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Ribonuclease T2 (EC 3.1.27.1, ribonuclease II, base-non-specific ribonuclease, nonbase-specific RNase, RNase (non-base specific), non-base specific ribonuclease, nonspecific RNase, RNase Ms, RNase M, RNase II, Escherichia coli ribonuclease II, ribonucleate nucleotido-2'-transferase (cyclizing), acid ribonuclease, RNAase CL, Escherichia coli ribonuclease I' ribonuclease PP2, ribonuclease N2, ribonuclease M, acid RNase, ribonnuclease (non-base specific), ribonuclease (non-base specific), RNase T2, ribonuclease PP3, ribonucleate 3'-oligonucleotide hydrolase, ribonuclease U4) is an enzyme.[1][2][3][4] This enzyme catalyses the following chemical reaction

Two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates

See also

References

  1. Garcia-Segura, J.M.; Orozco, M.M.; Fominaya, J.M.; Gavilanes, J.G. (1986). "Purification, molecular and enzymic characterization of an acid RNase from the insect Ceratitis capitata". Eur. J. Biochem. 158 (2): 367–372. doi:10.1111/j.1432-1033.1986.tb09760.x. PMID 3732273.
  2. Heppel, L.A.; Davies, D.R. (1966). "Pig liver nuclei ribonuclease". In Cantoni, G.L. Procedures in Nucleic Acid Research. New York: Procedures in Nucleic Acid Research. pp. 31–36.
  3. Reddi, K.K.; Mauser, L.J. (1965). "Studies on the formation of tobacco mosaic virus ribonucleic acid. VI. Mode of degradation of host ribonucleic acid to ribonucleosides and their conversion to ribonucleoside 5-phosphates". Proc. Natl. Acad. Sci. USA. 53 (3): 607–613. doi:10.1073/pnas.53.3.607. PMC 336984Freely accessible. PMID 14338240.
  4. Uchida, I.; Egami, F. (1967). "The specificity of ribonuclease T2". J. Biochem. (Tokyo). 61 (1): 44–53. PMID 6048969.
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