Thioesterases exhibit Esterase activity (splitting of an ester into acid and alcohol, in the presence of water) specifically at a thiol group.
Thioesterases or thiolester hydrolases are identified as members of E.C.3.1.2.
Ubiquitin thiolesterase is a well-known example, whose structure has been analyzed.
- Brocker, C; Carpenter, C; Nebert, DW; Vasiliou, V (Aug 2010). "Evolutionary divergence and functions of the human acyl-CoA thioesterase gene ( ACOT ) family.". Human Genomics. 4 (6): 411–20. PMC 3525216. PMID 20846931.
- thioesterase I at the US National Library of Medicine Medical Subject Headings (MeSH)
- thioesterase II at the US National Library of Medicine Medical Subject Headings (MeSH)